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The EVACO Project: A new battery for assessing social cognition disorders and related psychiatric disability in schizophrenia
- P. Roux, M. Urbach, S. Fonteneau, B. Aouizerate, F. Berna, L. Brunel, D. Capdevielle, I. Chereau, J. Danion, J. Dorey, C. Dubertret, J. Dubreucq, C. Faget, F. Gabayet, P.M. Llorca, J. Mallet, D. Misdrahi, R. Rey, R. Richieri, F. Schürhoff, H. Yazbek, C. Passerieux, E. Brunet-Gouet, FACE-SCZ-Group
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- Journal:
- European Psychiatry / Volume 33 / Issue S1 / March 2016
- Published online by Cambridge University Press:
- 23 March 2020, p. S78
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- Article
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The relation of social cognitive disorders and schizophrenic symptoms are well-established. Yet, assessment methods have not reached a consensus. In addition, causal paths between neurocognition, social cognition, symptoms and functional expression are not clearly understood. During the past few years, some authoritative accounts proposed specialized batteries of tests and emphasized theory of mind, emotion recognition, and interpretation bias constructs:
– NIMH's “Social cognition psychometric evaluation” battery (Pinkham AE, Penn DL, Green MF, Harvey PD. Schizophrenia Bulletin, 2015);
– “Social cognition and functioning in schizophrenia” (Green MF, Lee J, Ochsner KN. Schizophrenia Bulletin, 2013).
Interestingly, these accounts stemming either from expert consensus and psychometric considerations or from neuroscience knowledge recognized some difficulties in providing a fully usable set of instruments. The project described here (EVACO protocol, funded by the Programme Hospitalier de Recherche Clinique national) follows an alternative approach and aims at providing a psychometrically validated battery. Based on a cognitive neuropsychology view on schizophrenic functional disability, several tests were gathered and are assessed in a 12-months multi-center follow-up of 160 individuals with schizophrenia. The FondaMental foundation network of Expert Centers is involved in recruiting patients from eight centers (Clermont-Ferrand, Colombes, Créteil, Grenoble, Marseille, Montpellier, Strasbourg, Versailles). To-date, the first evaluation of the population has been achieved. Experience reports and inclusions follow-up demonstrate the good acceptability of this battery both on the patients and the evaluator's side. We emphasize the usefulness of this project to meet the clinicians’ needs of validated social cognition tools, by describing different scenarios of use.
Disclosure of interestThe authors have not supplied their declaration of competing interest.
5 - Complex fluids
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- By I. Aranson, D. Blair, P. Vorobieff, G. Metcalfe, T. Shinbrot, J. J. McCarthy, J. M. Ottino, J. S. Olafsen, J. S. Urbach, R. Mikkelsen, M. Versluis, E. Koene, G.-W. van der Bruggert, D. Lohse, M. Tirumkudulu, A. Tripathi, A. Acrivos, J. H. Walther, S.-S. Lee, P. Koumoutsakos, I. Eames, S. B. Dalziel, S. L. Anna, H. Spiegelberg, G. H. McKinley
- M. Samimy, Ohio State University, K. S. Breuer, Brown University, Rhode Island, L. G. Leal, University of California, Santa Barbara, P. H. Steen, Cornell University, New York
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- Book:
- A Gallery of Fluid Motion
- Published online:
- 25 January 2010
- Print publication:
- 12 January 2004, pp 54-62
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Summary
Interface motion in a vibrated granular layer
Granular materials are now recognized as a distinct state of matter, and studies of their behavior form a fascinating interdisciplinary branch of science. The intrinsic dissipative nature of the interactions between the constituent macroscopic particles gives rise to several basic properties specific to granular substances, setting granular matter apart from the conventional gaseous, liquid, or solid states.
Thin layers of granular materials subjected to vertical vibration exhibit a diversity of patterns. The particular pattern is determined by the interplay between driving frequency f and the acceleration amplitude Γ. Interfaces in vibrated granular layers, existing for large enough amplitude of vibration, separate large domains of flat layers oscillating with opposite phase. These two phases are related to the period-doubling character of the flat layer motion at large plate acceleration. Interfaces are either smooth or “decorated” by periodic undulations depending on parameters of vibration. An additional subharmonic driving results in a controlled displacement of the interface with respect to the center of the experimental cell. The speed and the direction of the interface motion are sensitive to the phase and amplitude of the subharmonic driving.
The image sequence above shows interface nucleation and propagation towards the center of the cell, with dimensionless time tf labeled in each image. The interface forms at the right side wall of the cell due to small-amplitude phase-shifted subharmonic driving. After the additional driving stops, the interface moves towards the center, creating small-scale localized structures in the process.
Experimental and numerical studies of an eastward jet over topography
- YUDONG TIAN, ERIC R. WEEKS, KAYO IDE, J. S. URBACH, CHARLES N. BAROUD, MICHAEL GHIL, HARRY L. SWINNEY
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- Journal:
- Journal of Fluid Mechanics / Volume 438 / 10 July 2001
- Published online by Cambridge University Press:
- 05 July 2001, pp. 129-157
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Motivated by the phenomena of blocked and zonal flows in Earth's atmosphere, we conducted laboratory experiments and numerical simulations to study the dynamics of an eastward jet flowing over wavenumber-two topography. The laboratory experiments studied the dynamical behaviour of the flow in a barotropic rotating annulus as a function of the experimental Rossby and Ekman numbers. Two distinct flow patterns, resembling blocked and zonal flows in the atmosphere, were observed to persist for long time intervals.
Earlier model studies had suggested that the atmosphere's normally upstream- propagating Rossby waves can resonantly lock to the underlying topography, and that this topographic resonance separates zonal from blocked flows. In the annulus, the zonal flows did indeed have super-resonant mean zonal velocities, while the blocked flows appear subresonant. Low-frequency variability, periodic or irregular, was present in the measured time series of azimuthal velocity in the blocked regime, with dominant periodicities in the range of 6–25 annulus rotations. Oscillations have also been detected in zonal states, with smaller amplitude and similar frequency. In addition, over a large region of parameter space the two flow states exhibited spontaneous, intermittent transitions from the one to the other.
We numerically simulated the laboratory flow geometry in a quasi-geostrophic barotropic model over a similar range of parameters. Both flow regimes, blocked and zonal, were reproduced in the simulations, with similar spatial and temporal characteristics, including the low-frequency oscillations associated with the blocked flow. The blocked and zonal flow patterns are present over wide ranges of forcing, topographic height, and bottom friction. For a significant portion of parameter space, both model flows are stable. Depending on the initial state, either the blocked or the zonal flow is obtained and persists indefinitely, showing the existence of multiple equilibria.